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Depression: A Risk Factor for Non-cardiovascular and Cardiovascular Disease
Here are some of what Cousins Center investigators have found:
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| Depression alters the immune system and risk for infectious disease. |
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Irwin M: Immune correlates of depression. Advances in Experimental Medicine and Biology 461:1-24, 1999. |
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Irwin M, Costlow C, Williams H, Artin KH, Chan CY, Stinson D, Levin MJ, Hayward AR,Oxman M: Cellular immunity to varicella-zoster virus in patients with major depression. J Infectious Diseases 178 (Suppl 1):S104-108, 1998. |
| Depression leads to inflammation: role in cardiovascular disease |
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Lesperance F, Frasure-Smith N, Theroux P, Irwin M . The association between major depression and levels of soluble intercellular adhesion molecule 1, interleukin-6, and C-reactive protein in patients with recent acute coronary syndromes. Am J Psychiatry 161(2): 271-7, 2004. |
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Gage, J. R., G. C. Fonarow, M. Hamilton, O. Martínez-Maza, and D. L. Vredevoe. 2004. Beta blocker and Angiotensin-converting enzyme inhibitor therapy is associated with decreased Th1/Th2 cytokine ratios and inflammatory cytokine production in patients with chronic heart failure. Neuroimmunomodulation 11:173-180. |
| The utility of yoga asanas in decreasing symptoms of depression and improving mood |
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Woolery A, Myers H, Sternlieb B, Zeltzer LK: A yoga intervention for young adults with elevated symptoms of depression, Alternative Therapies in Health & Medicine, 2004; 10, 60-63. |
| Immune activation and depression predict disease severity in rheumatoid arthritis patients |
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Zautra AJ, Yocum DC, Villanueva I, Smith B, Davis MC, Attrep J, Irwin M. Immune activation and depression in women with rheumatoid arthritis. J Rheumatol 31 (3):457-63, 2004. |
| Inflammatory Markers and Sleep Disturbance in Major Depression |
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Motivala , S.J., Sarfatti, A., Olmos, L., & Irwin, M. (in press). Inflammatory Markers and Sleep Disturbance in Major Depression. Psychosomatic Medicine. |
| Here are some of our ongoing studies: |
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Depression and Trial of Varicella Vaccine in the Elderly - Click here
Michael Irwin, Principal Investigator |
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New PDF in the Psychosomatic Medicine Journal |
