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| Aging: Older adults may be especially vulnerable to the immunological effects of stress. Here is what Center investigators have found: |
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| Solutions to the development of vaccine in the elderly | |
| • | Effros RB. Problems & solutions to development of vaccines for the elderly, Immunol Allergy Clin North Am 2003 Feb;23(1):41-55 |
| The practice of Tai Chi Chih, a moving meditation, improves health functioning and immunity in older adults. | |
| • | Irwin MR, Pike JL, Cole, JS & Oxman M . Effects of a behavioral intervention, Tai Chi Chih, on Varicella zoster virus specific immunity and health functioning in older and at-risk adults. Psychosomatic Medicine, 65:824-830, 2003. |
| Bereavement in Alzheimer caregivers has health consequences | |
| • | Grant I, Adler KA, Patterson TL, Dimsdale JE, Ziegler MG, Irwin MR. Health consequences of Alzheimer caregiving transitions: effects of placement and bereavement. Psychosomatic Medicine 64:477-486, 2002. |
| Genetic modulation serves as a novel strategy to augment immune function in the elderly | |
| • | Effros RB. Genetic alterations in the ageing immune system: impact on infection and cancer. Mech Ageing Dev. 2003 Jan;124(1):71-7. |
| Sleep impairs health | |
| • | Motivala SJ, Levin MJ, Oxman MN, Irwin MR. Impairments in health functioning and sleep quality in older adults with a history of depression. JAGS 2006 54:1184-1191. http://www.blackwell-synergy.com/doi/full/10.1111/j.1532-5415.2006.00819.x |
| See what we are doing now. Here are some of our ongoing studies | |
| • | Enhancing Recovery After Cardiac Surgery PI: Lynn Doering Funded by NINR |
| • | CD8 T Cell Replicative Senescence: Impact on Aged Humans PI: Rita Effros Funded by NIA |
| • | Aging: Cytokine Mechanisms and Treatment of Insomnia PI: Michael Irwin Funded by NIA |
| • | Sleep and Immune Mechanisms in Rheumatoid Arthritis PI: Michael Irwin Funded by NHLBI |
| • | Intervention Clinical Trial for Geriatric Depression PI: Helen Lavretsky Funded by NIMH |
| • | Aging: Insomnia Treatment and Energy Balance PI: Sarosh Motivala Funded by NIA |
| • | Psychological and Biological Antecedents of Health Behavior Decisions PI: Shelley Taylor Funded by NIA |
| Research : | Sponsored Studies : | Aging |
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