About Us : | Faculty : | Naliboff |
Bruce D. Naliboff, Ph.D. Clinical Professor, Department of Psychiatry and Biobehavioral Sciences, at the David Geffen School of Medicine, UCLA Co-Director, UCLA Center for Integrative Medicine Director, Human Physiological Reserach, CNS: Center for Neurovisceral Sciences and Women's Health, UCLA Division of Digestive Diseases Chief, Psychophysiology Research Laboratory, VA Greater Los Angeles Healthcare System Senior Research Scientist, Cousins Center for Psychoneuroimmunology, UCLA Neuropsychiatric Institute Research Interests Dr. Naliboff’s research has focused on psychophysiological mechanisms of stress and pain. Past studies have addressed how stress impacts the immune system, glucose regulation in diabetes, and cardiovascular variables. He has also studied psychosocial and personality variables in chronic pain and especially their impact on treatment choice and outcome. |
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Dr. Naliboff conducts etiologic and treatment studies of functional gastrointestinal disorders such as Irritable Bowel Syndrome (IBS). These include perceptual, autonomic, and brain imaging studies of visceral sensation, and the role of psychosocial variables in the presentation, course and treatment of IBS. A major emphasis of his current work is the relationship between central stress mechanisms and both somatic and visceral pain disorders. Another area of interest is in the relationship between anxiety and symptoms in chronic pain disorders. Dr. Naliboff has NIH funding to study gender differences in central responses to visceral sensation as well as the role of visceral specific anxiety in Irritable Bowel Syndrome. He has recently begun a clinical trial comparing several psychological treatments for IBS and has an ongoing clinical trial of opioid medications in of chronic pain. He collaborates with other UCLA investigators on studies of neuroendocrine and immune factors in pain conditions such as IBS and fibromyalgia.
Current research Health Outcomes from Opiate Therapy for Chronic Pain Treatment of Pain and Fear in Irritable Bowel Syndrome Recent publications Naliboff BD, Solomon GF, Gilmore S, Benton D, Fahey JL, Pine J. Rapid changes in cellular immunity following a confrontational role-play stressor. Brain Behavior and Immunity 9: 207-219, 1995. Lembo A, Naliboff BD, Matin K, Munakata J, Parker R, Gracely R, Mayer EA. Irritable bowel syndrome patients show altered sensitivity to exogenous opioid. Pain, 1195-1200, 2000. Naliboff BD, Derbyshire SWG, Munakata J, Berman S, Mandelkern M, Chang L, Mayer EA. Cerebral activation in irritable bowel syndrome patients and control subjects during rectosigmoid distension. Psychosomatic Medicine, 63: 365-375, 2001. Cole SW, Naliboff BD, Kemeny ME, Griswold M, Fahey JL, & Zack JA. Impaired response to HAART in HIV-infected individuals with high autonomic nervous system activity . PNAS USA, 98, 12695-12700, 2001. Chang L, Munakata J, Naliboff B, Saba L, Matin K, Bernstein C, Anton PA, Mayer EA. Perceptual responses in patients with inflammatory and functional bowel disease. Gut, 47:497-505, 2000. Bruce D. Naliboff, Ph.D. |