|About Us :||Faculty :||Irwin|
|Michael Irwin, M.D.
Norman Cousins Professor
Department of Psychiatry & Biobehavioral Sciences
David Geffen School of Medicine, UCLA
Director & Senior Research Scientist
Cousins Center for Psychoneuroimmunology UCLA Neuropsychiatric Institute
Dr. Irwins principal research interests focus on the mechanisms of neuroimmune interactions and the impact of PNI processes on disease including infectious disease, rheumatoid arthritis, cardiovascular disease, and substance dependence. He has been the principal investigator of 14 federally funded research awards, including five currently active research awards from the National Institute of Mental Health, National Institute of Alcoholism and Alcohol Abuse, National Institute of Aging, National Institute of Arthritis and Musculoskeletal Disorders and the National Institute of Drug Abuse.
Selected Current Research
Alcoholism: Sleep and Cytokines in African Americans
|This study will advance our understanding
of the reciprocal relationships between cytokines and sleep in alcohol
dependence with implications for answering why sleep is disordered in
alcoholic patients and for the development of novel treatments for sleep
disturbance in alcoholism.
Depression and Trial of Varicella Vaccine
in the Elderly
Behavioral Intervention for Herpes Zoster
Risk in Aging
Irwin, M., G. Rinetti, et. al. (2004). “ Nocturnal proinflammatory cytokine-associated sleep disturbances in abstinent African American alcoholics.” Brain Behav Immun 18(4): 349-60.
Irwin, M.R. and G. Rinetti (2004). “Disordered sleep, nocturnal cytokines, and immunity: interactions between alcohol dependence and African-American ethnicity.” Alcohol 32(1): 53-61.
Lesperance, F., N. Frasure-Smith, et al. (2004). “The association between major depression and levels of soluble intercellular adhesion molecule 1, interleukin-6, and C-reactive protein in patients with recent acute coronary syndromes. “ Am J Psychiatry 161(2): 271-7.
Redwine, L., J. Dang, et al. (2004). “Cellular adhesion molecule expression, nocturnal sleep, and partial night sleep deprivation.” Brain Behav Immun 18(4): 333-40.
Zautra, A J., D.C. Yocum, et al. (2004). “Immune activation and depression in women with rheumatoid arthritis.” J Rheumatol 31(3):457-63.