Research : Sponsored Studies : Infectious Diseases & HIV / AIDS
Infectious Disease: Psychological and Biological Mechanisms of Disease Risk

Here is what Cousins Center investigators have found:

Psychological risk factors can increase autonomic activation and lead to increases of viral load in patients with human immunodeficiency virus (HIV)
Cole SW, Kemeny ME, Fahey JL, Zack JA and Naliboff BD. (in press) Psychological risk factors for HIV pathogenesis: Mediation by the autonomic nervous system. Biological Psychiatry.
Cole SW, Naliboff BD, Kemeny ME, Griswold M, Fahey JL & Zack JA. (2001) Impaired response to HAART in patients with high autonomic nervous system activity. Proceedings of the National Academy of Sciences of the USA, 98, 12695-12700
Depression lowers immunity to herpes zoster or shingles
Irwin M, Costlow C, Williams H, Artin KH, Chan CY, Stinson D, Levin MJ, Hayward AR,Oxman M: Cellular immunity to varicella-zoster virus in patients with major depression. J Infectious Diseases 178 (Suppl 1):S104-108, 1998.
A mind-body intervention, Tai Chi Chih, improves immunity to varicella zoster virus with implications for resistance to shingles in older adults.
(forthcoming in Psychosomatic Medicine)
Post-operative infections are more likely to occur in alcoholics with abnormal cytokine expression.
Sanders M, Irwin M, Sinha P, Naumann E, Kern H, Kox WJ, Spies CD: Suppresion of Interleukin-6 to interluekin-10 ratio in chronic alcoholics: association with postoperative infections. Intensive Care Med 28:285-292, 2002. (8 pages)
See what we are doing now. Here are some of our ongoing studies:
Autonomic Nervous System Control of HIV-1 Replication - Click here
Steven W. Cole, Principal Investigator
Behavioral Intervention for Herpes Zoster Risk in Aging - Click here
Michael Irwin, Principal Investigator
Alcoholism: Sleep and Cytokines - Click here
Michael Irwin, Principal Investigator
Cocaine: Sleep and Cytokines - Click here
Michael Irwin, Principal Investigator
Study Participation
Sponsored Studies
Seed Grant Program
Core Laboratories